It is important to discuss the use of all medications, vitamins and supplements with your physician. High doses of myo-inositol may have additive effects when taken concurrently with selective serotonin reuptake inhibitor (SSRI) and selective serotonin norepinephrine reuptake inhibitor (SNRI) antidepressant medications. You should use caution when combining high doses of myo-inositol with herbal products like St. John’s wort. High doses of folic acid may result in decreased serum levels of the anticonvulsant drugs.
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