Slower to absorb: Ferrous iron is absorbed shortly after it is ingested. However, carbonyl iron is only absorbed at the rate that gastric acid is produced, since gastric acid is required to make carbonyl iron soluble. This means carbonyl iron enters the system much more gradually than other types of iron that can dissolve rapidly, meaning carbonyl iron has a more prolonged absorption period.
Less toxic than ferrous iron: Researchers believe this slow rate of solubilization minimizes the toxicity of carbonyl iron. In fact, studies have shown carbonyl iron is far less toxic than other forms of iron, even at high doses. Patients taking carbonyl iron can tolerate 10 to 150 times the standard dose of ferrous sulfate iron, while still having nearly the same side effects. Due to its slower absorption, carbonyl iron may have an advantage over therapy with iron salts by substantially reducing or eliminating the risk of poisoning in children.
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